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구성원

교수진

김성은 D

김성은

  • 직위 부교수
  • 연구분야 Cancer metabolism; Macropinocytosis; Autophagy; Cell death; Ferroptosis; Entosis
  • 전화번호 02-3290-5647
  • 연구실 하나과학관 B동 165호
  • 홈페이지 https://kimlab-ku.weebly.com/open_in_new
  • 이메일 sek19@korea.ac.kr

학력

BS (2002-2006), Biotechnology and Genetic Engineering, Korea University, South Korea
MS (2006-2008), Animal Biotechnology and Genetic Engineering, Korea University, South Korea
PhD (2009-2016), BCMB (Biochemistry, Cell, and Molecular Biology) Allied Program, Weill Cornell & MSKCC, USA
Postdoctoral Fellow (2016-2019), University of California, San Francisco, USA

연구논문

·  Wang MT, Fer N, Galeas J, Collisson EA, Kim SE, Sharib J, McCormick F. Blockade of leukemia inhibitory factor as a therapeutic approach for KRAS-mediated pancreatic cancer. Nat Commun. 2019. PMID: 31296870. 

·  Hamann JC, Kim SE, Overholtzer M. Methods for the study of entotic cell death. Methods Mol Biol. 2019. PMID: 30610714.

·  Hawk MA, Gorsuch CL, Fagan P, Lee C, Kim SE, Hamann JC, Mason JA, Weigel KJ, Tsegaye MA, Shen L, Shuff S, Zuo J, Hu S, Jiang L, Chapman S, Leevy WM, DeBerardinis RJ, Overholtzer M, Schafer ZT. RIPK1-mediated induction of mitophagy compromises the viability of extracellular-matrix-detached cells. Nat Cell Biol. 2018. PMID: 29459781.

·  Kim SE, Zhang L, Ma K, Riegman M, Chen F, Ingold I, Conrad M, Turker MZ, Gao M, Jiang X, Monette S, Pauliah M, Gonen M, Zanzonico P, Quinn T, Wiesner U, Bradbury MS, Overholtzer M. Ultrasmall nanoparticles induce ferroptosis in nutrient-deprived cancer cells and suppress tumor growth. Nat Nanotechnol. 2016. PMID: 27668796.

·  Florey O, Kim SE, Overholtzer M. Entosis: cell-in-cell formation that kills through entotic cell death. Curr Mol Med. 2015. PMID: 26511711.

·  Florey O, Gammoh N, Kim SE, Jiang X, Overholtzer M. V-ATPase and osmotic imbalances activate endolysosomal LC3 lipidation. Autophagy. 2015. PMID: 25484071.

·  Kim SE, Overholtzer M. Autophagy proteins regulate cell engulfment mechanisms that participate in cancer. Semin Cancer Biol. 2013. PMID: 23726896.

·  Kim SE, An SY, Woo DH, Han J, Kim JH, Jang YJ, Son JS, Yang H, Cheon YP, Kim JH. Engraftment potential of spheroid-forming hepatic endoderm derived from human embryonic stem cells. Stem Cells Dev. 2013. PMID: 23373441.

·  Woo DH, Kim SK, Lim HJ, Heo J, Park HS, Kang GY, Kim SE, You HJ, Hoeppner DJ, Kim Y, Kwon H, Choi TH, Lee JH, Hong SH, Song KW, Ahn EK, Chenoweth JG, Tesar PJ, McKay RD, Kim JH. Direct and indirect contribution of human embryonic stem cell-derived hepatocyte-like cells to liver repair in mice. Gastroenterology. 2012. PMID: 22138358.

·  Florey O, Kim SE, Sandoval CP, Haynes CM, Overholtzer M. Autophagy machinery mediates macroendocytic processing and entotic cell death by targeting single membranes. Nat Cell Biol. 2011. PMID: 22002674.

·  Lim HJ, Han J, Woo DH, Kim SE, Kim SK, Kang HG, Kim JH. Biochemical and morphological effects of hypoxic environment on human embryonic stem cells in long-term culture and differentiating embryoid bodies. Mol Cells. 2011. PMID: 21347709.

·  Gil JE, Woo DH, Shim JH, Kim SE, You HJ, Park SH, Paek SH, Kim SK, Kim JH. Vitronectin promotes oligodendrocyte differentiation during neurogenesis of human embryonic stem cells. FEBS Lett. 2009. PMID: 19162023.

·  Shim JH, Kim SE, Woo DH, Kim SK, Oh CH, McKay R, Kim JH. Directed differentiation of human embryonic stem cells towards a pancreatic cell fate. Diabetologia. 2007. PMID: 17457565.

·  Kim SE, Kim BK, Gil JE, Kim SK, Kim JH. Comparative analysis of the developmental competence of three human embryonic stem cell lines in vitro. Mol Cells. 2007. PMID: 17464211.

·  Kim BK, Kim SE, Shim JH, Woo DH, Gil JE, Kim SK, Kim JH. Neurogenic effect of vascular endothelial growth factor during germ layer formation of human embryonic stem cells. FEBS Lett. 2006. PMID: 17027979.
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